U.S. Full Prescribing Information Medication Guide Indication U.S. Healthcare Professionals |En Español
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1-888-SOTYKTU
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INFO TO HELP
YOU GET STARTED

INFO TO HELP
YOU GET STARTED

READY TO GO? YOU CAN GET STARTED ON YOUR TREATMENT PATH WITH THESE 3 STEPS:
SOTYKTU™ 360 SUPPORT logo

Once you and your dermatologist decide if SOTYKTU is right for you, here are some steps to get started:

STEP 1: Complete your enrollment form to learn how you may be able to access therapy and affordability options for eligible patients, including the SOTYKTU Co-Pay Assistance Program
STEP 2: Answer the phone call from your dedicated SOTYKTU Support Coordinator
STEP 3: Set up your first prescription shipment

Scroll down for more important details

STEP 1: Complete your enrollment form
(aka SOTYKTU Start Form)
Enroll in SOTYKTU 360 SUPPORT with your dermatologist and save our number to your phone.
Add our number to your phone-that way you'll always know when it's your SOTYKTU Coordinator calling.

Save our number to your phone: 1-888-SOTYKTU (768-9588) and add SOTYKTU 360 SUPPORT to your contacts
DOWNLOAD START FORM
DOWNLOAD (EN ESPAÑOL)
Other information you may want to know:
Receive your prescription for SOTYKTU
Your dermatologist will let you know if you need to complete any tests before starting SOTYKTU
Free Trial:
First-time patients may be eligible to receive a free trial of SOTYKTU*
Determine prescription coverage
We’ll begin to figure out your insurance coverage for SOTYKTU.†
Step 2: Answer the call from your Support Coordinator
Your SOTYKTU Support Coordinator will call you after you enroll to welcome you to SOTYKTU 360 SUPPORT and answer any questions you have about access and affordability. Ask about the SOTYKTU Co-Pay Assistance Program to see if you're eligible or already registered.†‡
If you don’t receive a call, give your dermatologist's office a ring to make sure you were enrolled.
Other information you may want to know:
Prescription coverage notification
Your SOTYKTU Support Coordinator can help you figure out your pharmacy benefit coverage.
Know your benefits
Ask your SOTYKTU Support Coordinator about these offers:
  • The SOTYKTU Bridge Program§ could be your crossover to coverage. If you’re an eligible commercially insured patient and SOTYKTU isn’t initially covered by your insurance, you may be able to receive SOTYKTU free of charge for up to 3 years while you await a coverage decision.
  • The SOTYKTU Co-Pay Assistance Program
    Eligible commercially insured patients may pay as little as $0 a month* for SOTYKTU. Click here to learn more.
Step 3: Arrange your first at-home prescription shipment
Your prescription will be mailed to you one of two ways:
  • Directly from the SOTYKTU 360 SUPPORT Pharmacy.
  • From a specialty pharmacy, which is a mail order pharmacy that carries specialty medicines (like SOTYKTU) not typically carried by your local pharmacy.
Other information you may want to know:
Sign up for SOTYKTU 360 SUPPORT emails
Enroll here or call 1-888-
SOTYKTU (768-9588) to be
better prepared to start treatment and find encouragement along the way with these helpful emails. Already enrolled? No need to sign up again if you receive a confirmation email from SOTYKTU (deucravacitinib) 360 SUPPORT.
Keep taking SOTYKTU as prescribed by your dermatologist
Find tips for taking SOTYKTU here
Continue to set up shipments for refills as long as you are prescribed SOTYKTU
Keep your scheduled follow-ups to continue on your path with SOTYKTU
*SOTYKTU Free Trial Offer and Co-Pay Assistance Program Terms and Conditions.
†Completion of any reimbursement- or coverage-related paperwork is the responsibility of the healthcare provider and the patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.
‡While support team members can answer questions about SOTYKTU, they cannot provide medical advice.
§Please see SOTYKTU Bridge Program Terms and Conditions.
SUPPORT FROM
THE START
Here’s where you can learn about all the resources that may be available to you through SOTYKTU 360 SUPPORT. This support may help you along your treatment path.
Hypothetical SOTYKTU™ (deucravacitinib) patient with moderate to severe plaque psoriasis Hypothetical SOTYKTU™ (deucravacitinib) patient with moderate to severe plaque psoriasis
MAKE SOTYKTU A PART OF YOUR DAILY ROUTINE
It’s important to take SOTYKTU as prescribed by your doctor—once
daily, every day. Learn more about starting and taking SOTYKTU.
MORE ABOUT ONCE-DAILY DOSING
Important Facts About
SOTYKTU™
(deucravacitinib)
This is a summary of important information that you need to know about SOTYKTU. Your dermatologist can work with you to help answer any questions you may have about this medication. Keep this information in a safe place, so you can refer to it before and during your treatment.
This is a summary of important information that you need to know about SOTYKTU. Your dermatologist can work with you to help answer any questions you may have about this medication. Keep this information in a safe place, so you can refer to it before and during your treatment.
Look out for the following icons as you read:
Talk to your dermatologist
Call a dermatologist right away
Helpful information to remember
What is SOTYKTU?
SOTYKTU is an oral prescription medication that is used to treat:
Moderate-to-severe plaque psoriasis in adults who may benefit from systemic therapy (pills or injections that work inside the body) or phototherapy (treatment using specialized ultraviolet or UV light).
It is not known if SOTYKTU is safe
and effective in children under 18
years of age.
What is the most important information I should know about SOTYKTU?
SOTYKTU may cause serious side effects, including:
Serious allergic reactions. Stop taking SOTYKTU and get emergency medical help right away if you develop
any of the following symptoms of a serious allergic reaction:
  • Feeling faint
  • Swelling of your face, eyelids,
    lips, mouth, tongue, or throat
  • Trouble breathing or
    throat tightness
  • Chest tightness
  • Skin rash, hives
Infections. SOTYKTU is a medicine that affects your immune system. SOTYKTU can lower the ability of your immune system to fight infections and can increase your risk of infections. Your dermatologist should check you for infections before starting SOTYKTU. Some people have had serious infections while taking SOTYKTU, such as infections of the lungs, including pneumonia and tuberculosis (TB) and COVID-19.
Before starting SOTYKTU, your dermatologist should check you for TB. If you have active TB or a history of TB, you may be treated for TB before beginning treatment with SOTYKTU. Your dermatologist should watch you closely for signs and symptoms of TB during treatment with SOTYKTU.
If you get a serious infection, your dermatologist may tell you to stop taking SOTYKTU until your infection is controlled.
Call or see a dermatologist if you notice any symptoms of TB.
Call or see a dermatologist right away if you have an infection or develop any new or worsening symptoms of an infection, including:
  • Fever, sweats, or chills
  • Muscle aches
  • Weight loss
  • Cough
  • Shortness of breath
  • Blood in your phlegm (mucus you cough up)
  • Warm, red, or painful skin or sores on your body different from your psoriasis
  • Diarrhea or stomach pain
  • Burning when you urinate or urinating more often than normal
  • Feeling very tired
SOTYKTU should not be used in people with an active, serious infection, including localized infections. You should not start taking SOTYKTU if you have any kind of infection unless your dermatologist tells you it is okay.
You may be at higher risk of developing shingles (herpes zoster).
Before starting SOTYKTU, tell your dermatologist if you:
  • Have any kind of infection or symptoms of an infection (see symptoms listed in “What is the most important information I should know about SOTYKTU?”), as SOTYKTU may lower the ability of your immune system to fight infections and may increase your risk of infections. Infections include:
    • Any infection for which you are currently being treated.
    • Any infection that will not go away or a history of infections that keep coming back.
    • Tuberculosis (TB), a type of lung infection. Tell your dermatologist if you have TB or have been in close contact with someone with TB.
    • Hepatitis B or C. Tell your dermatologist if you have or have had hepatitis B or C.
After you start taking SOTYKTU, call your dermatologist right away if you have an infection or symptoms of an infection. SOTYKTU can make you more likely to get infections or make any infections you have worse.
Cancer. Certain kinds of cancer including lymphoma have been reported in people taking SOTYKTU. Tell your dermatologist if you have ever had any type of cancer.
Muscle problems (rhabdomyolysis). SOTYKTU can cause muscle problems that can be severe. Treatment with SOTYKTU may increase the level of an enzyme in your blood called creatine phosphokinase (CPK) and can be a sign of muscle damage. Increased CPK is common in people taking SOTYKTU. Your dermatologist may tell you to stop taking SOTYKTU if the amount of CPK in your blood gets too high or if you have signs and symptoms of severe muscle problems. Tell your dermatologist right away if you have any of these signs or symptoms of severe muscle problems:
  • Unexplained muscle pain, tenderness, or weakness
  • Feeling very tired
  • Fever
  • Dark-colored urine
A serious side effect is a side effect that may require medical treatment or hospitalization, cause permanent damage, or be life-threatening or sometimes even fatal.
What should I discuss with my dermatologist before starting treatment?
Talk to your dermatologist about all of your medical conditions, including if:
  • You have liver or kidney problems.
  • You have high levels of fat in your blood (triglycerides).
Talk to your dermatologist if you have recently received or are scheduled to receive a vaccine (immunization).
During treatment with SOTYKTU, you should avoid receiving live vaccines (vaccines that use a small
amount of the weakened virus). Common live vaccines (among others) include:
  • Measles, mumps, and rubella (MMR)
  • Rotavirus
  • Smallpox
  • Chickenpox
  • Yellow fever
Talk to your dermatologist if:
You are pregnant or plan to become pregnant. It is not known if SOTYKTU can
harm your unborn baby.
You are breastfeeding or plan to breastfeed. It is not known if SOTYKTU passes
into your breast milk.
Tell your dermatologist if you become pregnant or think you are pregnant during treatment
with SOTYKTU. Report pregnancies to Bristol-Myers Squibb by calling 1-800-721-5072.
Talk to your dermatologist about all of the medications you are taking, including:
  • Prescription medicines
  • Over-the-counter medicines
  • Vitamins
  • Herbal supplements
Keep a list of them to show your dermatologist and pharmacist when you get a new medicine.
What are the possible side effects of SOTYKTU?
SOTYKTU may cause serious side effects, including:
  • Changes in certain laboratory test results. Changes in laboratory tests have happened in some people taking SOTYKTU. Your dermatologist may do blood tests before you start taking SOTYKTU and during treatment with SOTYKTU to check for the following:
    • Increased triglycerides. Too much fat in your blood can cause problems with your heart.
    • Increased liver enzymes. If your liver enzymes increase too much, your dermatologist may need to do additional tests on your liver and may tell you to stop taking SOTYKTU if they think that SOTYKTU is harming your liver.
  • Potential risks from Janus kinase (JAK) inhibition. SOTYKTU is a tyrosine kinase 2 (TYK2) inhibitor. TYK2 is in the JAK family. It is not known whether taking SOTYKTU has the same risks as taking JAK inhibitors. Increased risk of death (all causes) has happened in people who were 50 years of age and older with at least 1 heart disease (cardiovascular) risk factor who were taking a JAK inhibitor used to treat rheumatoid arthritis (RA) compared to people taking another medicine in a class of medicines called TNF blockers. SOTYKTU is not for use in people with RA.
What are the most common side effects of SOTYKTU?
The most common side effects of SOTYKTU include:
  • Common cold, sore throat, and sinus infection (upper respiratory infections)
  • Cold sores (herpes simplex)
  • Sores on the inner lips, gums, tongue, or roof of the mouth (canker sores)
  • Inflamed hair pores (folliculitis)
  • Acne
These are not all of the possible side effects of SOTYKTU.
Talk to your dermatologist, pharmacist, or other members of your healthcare team for more information about side effects. If you experience any side effects and would like to report them to the FDA, you can visit www.fda.gov/medwatch or call 1-800-FDA-1088.
How should I take SOTYKTU?
Take SOTYKTU exactly as your
dermatologist tells you.
Take 1 time every day
Can be taken with or without food
Do not crush, cut, or chew the SOTYKTU tablets
SOTYKTU is available as a 6 milligram (mg) pink, round pill.
Each pill is marked with “BMS 895” and “6 mg.”
Do not take SOTYKTU if you are allergic to deucravacitinib or any of the ingredients in SOTYKTU.
Inactive ingredients: anhydrous lactose, croscarmellose sodium, hypromellose acetate succinate, magnesium stearate, microcrystalline cellulose, and silicon dioxide
Pill coating inactive ingredients: polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, iron oxide red and yellow
How should I store SOTYKTU?
Store SOTYKTU at room temperature between 68°F to 77°F (20°C to 25°C).
Keep SOTYKTU and all medicines out of reach of children.
For more information, please see the U.S. Full Prescribing Information and Medication Guide for SOTYKTU.
Talk to your healthcare team for more information about this medication.
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SOTYKTU and SOTYKTU logo are trademarks of
Bristol-Myers Squibb Company.
All other trademarks are property of their respective owners.
© 2023 Bristol-Myers Squibb Company.
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SOTYKTU, SOTYKTU 360 SUPPORT, and SOTYKTU logo are trademarks of Bristol-Myers Squibb Company.
All other trademarks are property of their respective owners.
© 2023 Bristol-Myers Squibb Company.
1787-US-2200141 09/22
Legal Notice|Privacy Policy|
Your Privacy Choices |Site Map
This website is intended for U.S. residents
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